CK Pharmaceutical                                                                                                              Page 1 of 2
Protocol 3001
                                                                Example 1

                                                  Subject Characteristics at Study Entry

    __________________________________________________________________________________________________________________________________
                                       Treatment Regimen: BID                                   Treatment Regimen: TID
                        _____________________________________________________    _____________________________________________________
                        Treatment A        Treatment B        Total              Treatment A        Treatment B        Total
    __________________________________________________________________________________________________________________________________

    Gender
      Male               31/ 52 (59.6%)     32/ 53 (60.4%)     63/105 (60.0%)      8/ 11 (72.7%)      5/  7 (71.4%)     13/ 18 (72.2%)
      Female             21/ 52 (40.4%)     21/ 53 (39.6%)     42/105 (40.0%)      3/ 11 (27.3%)      2/  7 (28.6%)      5/ 18 (27.8%)

    Race
      White              40/ 52 (76.9%)     42/ 53 (79.2%)     82/105 (78.1%)     10/ 11 (90.9%)      6/  7 (85.7%)     16/ 18 (88.9%)
      Black              10/ 52 (19.2%)      9/ 53 (17.0%)     19/105 (18.1%)      1/ 11  (9.1%)      1/  7 (14.3%)      2/ 18 (11.1%)
      Asian/Oriental      2/ 52  (3.8%)      1/ 53  (1.9%)      3/105  (2.9%)      0/ 11  (0.0%)      0/  7  (0.0%)      0/ 18  (0.0%)
      Multiracial         0/ 52  (0.0%)      1/ 53  (1.9%)      1/105  (1.0%)      0/ 11  (0.0%)      0/  7  (0.0%)      0/ 18  (0.0%)

    Age (years)
      N                  52                 53                105                 11                  7                 18
      Mean               62.12              58.43              60.26              51.09              54.43              52.39
      SD                  8.661              8.632              8.801             10.483              8.848              9.751
      Median             59.50              58.00              59.00              50.00              52.00              51.00
      Min                43.00              44.00              43.00              38.00              42.00              38.00
      Max                80.00              79.00              80.00              72.00              64.00              72.00

    Height (cm)
      N                  52                 53                105                 11                  7                 18
      Mean              171.56             171.75             171.66             178.10             179.23             178.54
      SD                 11.826             12.612             12.171             12.559              5.749             10.235
      Median            172.45             170.20             171.50             177.80             179.80             178.80
      Min               142.20             147.30             142.20             160.00             171.50             160.00
      Max               207.00             203.20             207.00             193.00             186.20             193.00



    __________________________________________________________________________________________________________________________________
    Note: Age was calculated by ((date of consent-date of birth)/365.25); BMI was calculated by (weight(kg)/height(m)**2).



Data are simulated and do not represent any actual trials.
Pgm: G:\caz\xprint\example1.sas                                 Runtime: 11MAY2007 12:58 PM                                 Validated: Yes


CK Pharmaceutical                                                                                                              Page 2 of 2
Protocol 3001
                                                                Example 1

                                                  Subject Characteristics at Study Entry

    __________________________________________________________________________________________________________________________________
                                       Treatment Regimen: BID                                   Treatment Regimen: TID
                        _____________________________________________________    _____________________________________________________
                        Treatment A        Treatment B        Total              Treatment A        Treatment B        Total
    __________________________________________________________________________________________________________________________________

    Weight (kg)
      N                  52                 53                105                 11                  7                 18
      Mean               99.66             105.44             102.58             114.98             104.63             110.96
      SD                 23.222             20.790             22.113             25.470             13.543             21.755
      Median             98.85             104.10             102.00             117.00             105.40             109.55
      Min                54.10              66.00              54.10              67.70              88.90              67.70
      Max               167.40             175.30             175.30             157.90             125.60             157.90

    BMI (kg/m^2)
      N                  52                 53                105                 11                  7                 18
      Mean               33.89              35.96              34.94              36.73              32.47              35.07
      SD                  7.306              7.046              7.217              9.329              2.779              7.647
      Median             32.99              35.56              33.56              38.77              33.34              34.01
      Min                18.96              24.21              18.96              21.42              27.95              21.42
      Max                56.88              55.29              56.88              50.26              36.23              50.26













    __________________________________________________________________________________________________________________________________
    Note: Age was calculated by ((date of consent-date of birth)/365.25); BMI was calculated by (weight(kg)/height(m)**2).



Data are simulated and do not represent any actual trials.
Pgm: G:\caz\xprint\example1.sas                                 Runtime: 11MAY2007 12:58 PM                                 Validated: Yes